The Contribution Of The Chicago School Of Criminology Criminology Essay

The Contribution Of The Chicago School Of Criminology Criminology Essay To understand the contribution of the Chicago School of criminology is to understand how the confluence of geography, urbanisation, economics, immigration and the exchange of social theory between Europe and America combined to create new ways of looking at society. This essay will critically evaluate the contribution of the Chicago School, touching on these contributing factors to its development, prestige and influence. This essay will also note the limitations of the Chicago School that arise from the specificity of its location and its reliance on certain ideologies and research methods. In conclusion, this essay will argue that the same combination of factors that created the schools dominance in the field of criminology makes it vulnerable to social change. The Chicago School had its basis in the University of Chicago sociology department, which is the oldest in the United States and was established in 1892 (Lilly et al, 2007, p. 36). DEramo Thomson (2003) note this was a period of rapid social transformation. Chicago was a major railroad hub and became a huge industrial centre in its own right, notably its meat-packing industry (DEramo Thomson, 2003, p. 7). Chicago was an excellent place to carry out sociological fieldwork because it exemplified the post-industrial concentration of population in urban areas. The city grew from one million to two million people between 1890 and 1910 (Lilly et al, 2007, p. 34) providing a perfect Petri dish for the Chicago Schools study of human behaviour. The concentration of industry and therefore economic opportunity prompted an influx of immigrants and led to rapid changes in living patterns. Urbanisation was a major characteristic of the Industrial Revolution, and many cities grew very rapidly, so criminologists in other cities could easily generalise from the work of the Chicago School (Fine, 1995, p. 300). The most significant contribution of the Chicago School is the idea of social ecology. It holds that crime is a response to unstable environment and abnormal living conditions (Treadwell, 2006, p. 47). This is no longer a particularly radical idea, which is an indicator of the continued prominence of the Chicago School. For centuries, crime was viewed as a moral failure (ibid.) in the Judeo-Christian tradition. Criminals were sinners. What the Chicago School recognised was that urban life was distinct from rural life and its hectic, anonymous nature influenced peoples behaviour (Carrabine, 2004, p. 51). Chicago School criminologists were quick to draw a link between juvenile delinquency and the economic and geographic patterns of urban development. Thanks to the population boom they were able to study in detail, over a short span of time, the shifts from inner city to suburbs, and the differences in crime rates between affluent suburbs and the inner city poor (Treadwell, 2006). It is still possible to read first-hand observations in the Chicago School monographs written by sociologists such as Beirne and Thomas, on topics including hobos, prostitutes, dance halls and organised crime (Carrabine, 2004, p. 50). These books are a permanent testimony to the influence of the Chicago School, as well as offering a contemporary historical account of the development of criminology. Theories developed by the Chicago School are still central tenets of criminology whether modern researchers agree or are trying to discredit them. One of their primary assertions was that disruption, e.g. immigration, economic shifts and family instability, tends to cause crime, which has been affirmed by modern studies showing that social disorder, weak friendship networks and low community involvement produce higher crime rates (Lanier Henry, 2004, p. 214). Underlying the focus on identifying where crime is located geographically and socially is the influence of Emile Durkheim, who believed crime is an inevitable and necessary party of society (Beirne Messerschmidt, 2000, p. 97). This ideology naturally tends towards identifying crime and its causes, rather than believing it can be eliminated. The ongoing influence of the Chicago School prompted further sociological studies with a similar ethos of identifying where crime would come from. In the 1930s and 1940s sociological soc ial psychology, a study of group behaviour that emphasises group dynamics and socialisation (Siegel, 2008, p. 9), developed based in part on the Schools social ecology principles. Treadwell (2006) remarks that one of the Chicago Schools main contributions to criminology are its qualitative research methods. Robert Ezra Park, chair of the Department of Sociology, had a passion for walking the streets of the worlds great cities, observing the full range of human turbulence and triumphà ¢Ã¢â€š ¬Ã‚ ¦ he led a group of dedicated sociologists in direct, systematic observation of urban life (Carrabine, 2004, p. 50). Park taught his methods of direct observation to generations of students in his thirty-year career the University, ensuring the future study of criminology would be grounded in first-person observation. This seems axiomatic, however, it marked a shift from morally-determined ideas about crime that made assumptions based on belief, rather than observation. Sociologists such as Thresher and Shaw took to the streets, bars and juvenile courts of Chicago to observe people going about their daily lives (Treadwell, 2006). This pattern of study offered marginali sed people to report their own lives (ibid.). Subsequently research has tended to gravitate around methods pioneered by the Chicago School, such as direct interviews with subjects. This has also been construed as a weakness of the school, though, with critics arguing that the qualitative nature of its studies can result in the undue influence of the researchers personal bias (Fine, 1995, p. 139). While this inspired other sociologists to devote more attention to research techniques the subjectivist Chicago school method (ibid, p. 139) is still widely used in criminology. The structure of research in criminology has been shaped by the Chicago School in other ways, as well. It was home to some of the most influential voices in early criminology including urban sociologists such as W.I. Thomas, Robert Ezra Park, Ernest W. Burgess, and Louis Wirth (Siegel, 2008, p. 7) who pioneered social ecology. Significantly, Park, Burgess and Wirth were sociologists, teaching and conducting criminological research as part of the sociology department. As a result most criminologists have been trained in sociology, and many sociology departments are home to criminology courses (ibid. p. 162) This is more than an academic coincidence. To place criminology in the realm of sociology is to implicitly accept as a starting point the idea that criminal behaviour is rooted in society, not personal morality. This represents a radical shift from almost two thousand years of Judeo-Christian belief. In order to understand how important it is, imagine, for example, that criminology developed as an offshoot of economics. Not only would the style of research be vastly different, it seems likely the types of crime it studied would be different. White collar crime, such as fraud and embezzlement, might well be considered more serious and worthy of study than crimes against persons, such as assault or burglary. However, because criminology started with sociology the relationships between individuals, and between individuals and the larger culture, remain the primary subject of study. By focusing on relationships between people, and their environmental interactions, the Chicago School tended towards certain conclusions. Shaw McKay found that certain areas had consistently high delinquency rates despite rapid turnover of the population, this tended to support the idea that the environment itself was at least partly responsible for generating crime (Beirne Messerschmidt, 2000, p. 123). Furthermore, Shaw and McKay the first to identify what became known as white flight the phenomenon of well-off, well-educated (usually white) people moving out of urban centres to more affluent suburbs, leaving cities with concentrations of poor, less-educated citizens, often concentrated in ethnic or racial groups (ibid, p. 122). This pattern of movement and separation helps explain the observation that certain areas are more crime-prone. It is not the result of more criminals flocking to certain areas, but rather that the bad living conditions and poor infrastructure create barri ers community, and offer opportunities or even incentives for criminal behaviour. However, because of the sociological focus, what subsequent studies looked at were social concerns, rather than economic. Sutherland put forth the theory that criminal behaviour is learned, just like any other kind of behaviour (Hagan, 2007, p. 159). The learning takes place within groups, and includes learning how to commit criminal acts, and developing justifications for doing so (ibid.). This is based on the idea that if people are concentrated in areas with limited opportunity and/or close proximity to criminals, they are more likely to learn deviant behaviour. However, an equally valid line of reasoning would be all the people in a particular area are equally poor, so they turn to crime not as a learned behaviour but as an individual response to the economic conditions. Thanks to the Chicago School, though, the notion of learned criminal behaviour gained primacy. This can be seen in entertainment, like the film The Usual Suspects and TV drama Prison Break, whose plots involve groups of criminals brought together in prison who then plot and commit more crimes together. Despite making its main focus sociology the Chicago School does acknowledge that economics is the root of a great deal of criminal behaviour. Siegel (2008) argues the culture of poverty leads to apathy, cynicism and a sense of (p. 163) though again that is a sociological analysis of an economic situation. Nevertheless, the extensive Chicago School studies involving marginalised classes such as prostitutes and gangs (Carrabine, 2004, p. 52) offered rich data and established patterns for further study. The methodology, if not the ideological starting point, remains extremely relevant to thinking on the causes of crime. That is not to overstate the importance of the Chicago School. As previously noted, Chicago in the early twentieth century underwent rapid change thanks to a combination of geographic and economic factors that is unlikely to ever be repeated. The result is that some of the conclusions of the Chicago School, while interesting, are clearly limited in their usefulness. For example, the concentric rings theory of urban growth (Hagan, 2007, p. 154), which is based observations about Chicagos development with an industrial centre with layers of the poor, and then the increasingly affluent, around it. That development pattern applies to many American cities but, Beirne Messerschmidt note, is not equally valid in Europe (2000). Major European cities such as London, Paris, Barcelona and Amsterdam have extremely rich, desirable neighbourhoods close to the heart of the city, with poorer neighbourhoods scattered randomly around the outskirts. The Chicago School, working from its specific historical vantage point, failed to take into account different urban growth patterns. Even more critical is the consideration of innovations in technology and communications, which has important implications for how environment is defined. The Chicago School offered a strong counterpoint to explanations that blamed individuals for their criminality (Lilly et al, 2007, p. 34) and focused on the influence of environment. However, they were studying an urban area before the age of mass communication. Contemporary application of Chicago School ideas has to take into account that the nature of technology and therefore the social ecology has changed. Urbanisation is still a powerful driving force and there is still extensive economic migration, but it does not occur at the same rate as in turn-of-the-century Chicago. Modern technology allows people to constantly network and communicate with people outside their physical environment which necessarily changes the definition of what constitutes their community. A migrant living in London might be isolated from their own cult ural group which the Chicago School would argue is a risk for increased criminal behaviour but they can go to an internet cafà © and video-chat with friends in the country of origin. So in an important way they are maintaining a community bond, and they are not disrupted in the same way a 1930s immigrant would have been. Where the influence of the Chicago School can still be felt is that it continues to define terms of study, such as environment, even if the nature of what is being studied has changed. Another area where the Chicago School is less useful is in terms of drawing up plans for preventing crime. Based on the belief that crime is a learned behaviour, caused by environment, it argued that it can in large part be prevented by social programmes (Carrabine, 2004, p. 52). However, Lanier and Henry (2004) note the Chicago School observed that one of the factors in social disorganisation, and therefore crime, was a lack of respect for authority and little faith in social organisations. This presents a catch-22. Social organisations cannot effectively combat crime if people them. The Chicago School does not offer any firm solutions for this problem. Informal social organisations such as churches, parent-teacher associations and sports programmes suggest one way of reaching communities, and these groups are seen to play a major role in reducing criminal behaviour (Lanier Henry, 2004, p. 218). Lanier Henry (2004) note, however, that formal social control in the form of policing is also essential to prevent crime, however this is observational rather than prescriptive. In conclusion, Chicago was a powerhouse of social and intellectual study throughout the twentieth century. Cassidy notes Chicago thinking greatly influenced policymaking in the U.S. and many other parts of the world (Cassidy, 2008, p. 28) however he is talking about the Chicago School of economics, rather than criminology. Cassidy writes about the upheaval within the economic school due to the global recession, and the discrediting of many of the Chicago School of Economics fundamental financial beliefs (ibid). This shows that even the most respected, established schools of academic thought can be critically undermined by social changes. By definition, it is only possible to study what already exists. Though the theories drawn up by the Chicago School regarding criminology make important observations and predictions those are subject to revision based on changes in society. The usefulness of theories and ideologies is ultimately rooted in the real-life. When a culture undergoes radic al changes there are inevitably challenges to accepted ways of thinking and to long-standing academic disciplines. For almost a century the Chicago School has held its place in criminology, but as society changes and its needs change this long tradition could also be displaced.

Technology Assisted Reproduction Essays -- Research Reproduction Essay

Technology Assisted Reproduction Introduction Reproduction is fundamental for the perpetuation of a species and therefore is a trait all species possess. Human reproduction is usually not viewed in this context. Extinction of humans is not considered a threat, but the ability to reproduce is an issue of meeting social expectations. Psychologist Dr. Helen Fisher states that society tends to pressure women into feeling that motherhood is their sole connection to being female (Rutter, 1996). Likewise, men are influenced by society into feeling that they need to perform their part by "planting the seed" (Rutter, 1996). Fisher's insight may only represent parts of the reason humans feel the need to reproduce. However, it is evident that the ability to conceive a child is an important issue for most married couples. Unfortunately, complications occur when couples are infertile. Recent developments in reproductive technology have provided alternative methods of reproduction that can greatly enhance an infertile couple's chances of conc eiving. However, there are ethical and legal issues that accompany the use of these reproductive technologies. It is the responsibility of everyone, especially Christians, to become informed of the options reproductive technology can provide as well as the legal and ethical issues involved with their use before taking appropriate action. Background Beginning at puberty, the human male makes millions of sperm a day and continues to do so for about the next 50 years. On the other hand, the human female is born with approximately one million eggs, which are all that she will ever have (Infertility, 1996). The onset of menstruation during adolescence signals the beginning of a cycle in which hormo... ...win births soar with popularity of fertility drugs." Discovery. http://detnews.com/1997/discover/9702/20/02170076.htm. (September 24, 1998). Nelson, J.B. (1973). Human Medicine: ethical perspectives on new medical issues. Minneapolis: Augsburg Publishing House. "Reproductive Medicines." (1998). Organon. http://www.fertility-net.com/medicines.html. (September 23, 1998). "Reproductive Technology." (1996). Better Health and Medical. http://www.betterhealth.com/HK/ArticleMain/0,1349,178-496-488,00.htm. (September 23, 1998). Rutter, V. T. (1996, March). "Who stole fertility?" Psychology Today. pp. 46-49. Thomasma, D. C. & Kushman, T. Eds. (1996). Birth to Death. New York: Cambridge University Press. Youngkin, Dr. (1997). "Fertility Drugs." Texas Medical Association. http://www.texmed.org/news_events/radio_spots/ne_may0697_30.htm. (September 24, 1998).

College Admissions Essay: Its Time to Make Children a Priority :: College Admissions Essays

It's Time to Make Children a Priority Much of society judges the relative importance of an occupation by the size of the income or the associated fame. In fact many people judge themselves in the same way. To me, this is a male way of seeing the world. It's all about status and mating rights when you get down to it. I am prepared to concede that at some point in humanity's past this was a fair measure of a job's importance. But in a world that is clearly overpopulated it no longer makes sense to judge solely based upon the propogation of the species. Our focus should now move to the quality of the next generation rather than it's quantity. It is therefore my opinion that the most important job in the world is child raising. Those people that contribute to the healthy mental and physical development of children into adults, are performing a vital service to society. Imagine what the world would be like if children were truly our top priority, as some politicians so glibly pronounce. We are so far from that point that my imagination struggles with this concept. Why are teachers amongst the lowest paid people in western society? Why is it next to impossible to find a good creche? Why are there more laws to protect the rights of criminals than to protect those of us that choose to give up career to tend to home and family? Why is it that the educational standard of high school graduates is dropping faster than gravity should allow? Now some people will be nodding their heads at this point and saying, "Yes, the government should be doing something about this." Well I say, what are YOU doing about it. Take back responsibility for the upbringing of your own children.

The Importance of Securing equipmen Essay

The ability to be accountable of army equipment is a task given to all Service members. It starts when we first enter basic training. We receive our first issued items from CIF in order to complete all of our task during basic training. We are responsible to inventory and maintain our gear until we are finished with basic training. It is expected that we turn in item that were received in a clean and serviceable condition. After Basic training we move on to AIT and later to our first Unit. As we progress with our military career we become responsible for more gear. Our Platoon leaders and commanders entrust us with more sensitive as we sign not just for our personal gear. We sign for radios, vehicle, Blue Force Trackers and many other items that cannot fall into the hands of the enemy. The loss of any equipment is costly, not only does it cost money but it take time away from the mission while you are waiting for much needed gear. The inability to maintain your equipment potential causes a mission failure or missing a movement. The best method to keep equipment secure is to always have it on your person. The problem with this method is it’s not always possible. Caring around everything would be a very tedious and inefficient process. The next best method is to keep your equipment under lock and key. Keeping that in mind the equipment should be left in a place where security is in place to guard those items. Of course some item will need different levels of security such as weapons. The loss of any equipment can lead to a loss in operational security. You don’t want information much less equipment to fall into enemy hands. This could potentially lead to a loss of life.

Medicines and drugs Essay

A drug or medicine is a chemical that alters incoming sensory sensations, mood or emotions, or physiological state. Painkillers, hallucinogens and alcohols are examples of drugs and medicines that alter incoming sensory sensations. Prozac and alcohol alter mood or emotions Steroids, cigarettes and heart medicines alter physiological state, including consciousness, activity level or coordination. Drugs such as antiseptics, antibiotics and antivirals are infection fighters; hormones and vitamins affect body chemistry or metabolism; stimulants, depressants, analgesics and anesthetics affect the central nervous system and the brain. It is also important to understand that the human body has great natural healing processes; some drugs just increase the rate of natural healing. Also, there could be a placebo effect, it is when a pharmacologically inert substance that make seems to help because the person taking the substance was told that it would work. Placebo effect is examined by giving sugar pills to one group of tests patients, and real drugs to another group (when they are not aware of which they receive). B.1.2: Outline the stages involved in research, development and testing of new pharmaceutical products. This takes a very long time and costs a fortune, and is often controlled by the government. Before drugs are tested on humans, they must be testing on various animals (start with small animals and then go to bigger ones). The range of effective doses, the doses in which side-effects arise and the lethal doses have to be determined. There are 3 phases then; clinical trial; clinical evaluation (more in depth analysis); human studies with more evaluation, Very few drugs make it to the market, and the development would have cost a lot. Sometimes, things can still go wrong, like Thalidomide. It was given to pregnant women to treat morning sickness, but it cause deformities in babies! Now it is still used, but to treat skin sores. B.1.3. Describe the different methods of administering drugs * Oral: Very convenient. However, it might not be reliable as the rate of absorption depends on drug concentration, stomach content and pH value. As most is absorbed in the small intestines, so the drug must survive the gastric acid. Therefore it often lays in time release capsules. * Rectal: Good when drug cannot be taken orally due to vomiting or because the drug is pH sensitive. * Inhalation: Rapid, as there are loads of blood vessels in the lungs, and therefore a drug would have a reliable effect. Good for general anaesthesia, and asthma medicine. * Parental o Just below the skin; slower than for intravenous. Used often for dental injections o Into muscles; for large doses, or when immediate response is not needed (vaccines etc). o Intravenous; almost instantaneous, but cannot be undone when injected! Fatty lipids may bind some kinds of drugs, so the drugs won’t leave the body so fast The half life of a drug is the time for half the dose in the body to be eliminated. B.1.4. Discuss the terms lethal dosage (LD50), tolerance and side effects. LD50 is the lethal dose for 50% of the population; and it varies a lot from drug to drug. When one is tolerant, then one has to take a larger dose in order to feel the wanted effects. Some people after often use of a drug becomes dependant on it; physically (they must have it to be able to function physically) or psychologically (they must have it to feel right). Tolerance doesn’t necessarily mean that one gets used to the harmful effects. Sometimes it is hard to know the difference between main effect and side effect. A drug has many effects, and some patients benefit from a few of those effects; then those are the main effects, and all the other are side effects. Someone else, with another disease may benefit from other effects, and then those become the main effects. There are always harmful effects too. The risk : benefit ratio should also be considered. B.2.1. State and explain how excess acidity in the stomach can be reduced by the use of different bases. Bases, most often metal oxides, hydroxides, carbonates or hydrogen carbonates are used as antacids. These react with acid in the stomach to adjust the pH value. The purpose of gastric acid is to kill off bacteria, and help in digestion. However, over-eating or stress stimulates more production of acid, causing discomfort. The active ingredients tend to be; this react only with HCl: Magnesium Oxide: Magnesium Hydroxide: Aluminium Hydroxide: Calcium Carbonate: Sodium Hydrogen Carbonate: Magnesium Trisilicate: Some of the products; Carbon dioxide is a gas. So a foaming agent has to be added to prohibit excessive belching. Also alginates are used, to prevent acid reflux. If too much antacid is used, the stomach becomes too basic, and that hurts too; then more antacid might be wrongly taken. This leads to alkalosis. B.3.2. Describe the use of derivatives of salicylic acid as mild analgesics and compare the advantages and disadvantages of using aspirin and paracetamol (acetaminophen) Salicylic acid is used as an anti-pyretic (fever reducer) and mild analgesic (painkiller), but it is a strong acid and hurts the stomach and mouth; so variations of salicylic acid was used. One is Acetyl Salicylic Acid (ASA) or Aspirin, which has the benefits of salicylic acid and does not irritate so much due to the acetyl group. When ASA reacts with water, it becomes salicylic acid, and the by-product of ethanoic acid. GOOD: It is good for killing minor pain, reducing fever, acting as an anti-inflammatory agent and prevents abnormal blood clot. BAD: Upsets stomach and bleeding; allergy; accidental poisoning in infants and Reye’s syndrome. Acetaminophen is also an anti-pyretic and analgesic. However it does not upset the stomach and is safe. However, overdose can still occur and lead to liver and brain damage. And it is not anti-inflammatory. Ibuprofen is like aspirin and cause fewer stomach problems. It is anti-inflammatory and is very safe. B.3.3. Compare the structures of morphine, codeine and the semi-synthetic opiate heroin. These are strong analgesics and are often called opiates, narcotics or narcotic analgesics. The major pain relieving substance originates from the opium poppy plant is sleep inducing and pain relieving. All three share the same skeleton. Remember the group C2H3O2 is called an acetyl group. B.3.4. Discuss the advantages and disadvantages of using morphine and its derivatives as strong analgesics. These affects: The Central Nervous System, the Eye and the Gastrointestinal tract (the digestive system) They are used as: Strong analgesics (severe pain from injury and chronic diseases); treatment of diarrhoea, relieve coughing. However they are very addictive and are rather replaced with something else. They also produce mood changes, drowsiness and mental clouding. Tolerance can arise by adaptation of the liver and neurons in the brain. Some people can’t function without the drug, feeling restlessness, sweating, fever, chills, vomiting, aches etc due to abstinence of the drug. There is often severe psychological dependence too (one might feel extremely depressed).’à ¯Ã‚ ¿Ã‚ ½ Short term effects: Sedation, stupor, pain relief, euphoria, reduced tension, worry, couching reflex. One might die of overdose. Long term effects: Loss of appetite, sterility, withdrawal illness, crime, diversion of energy. B.4.1. Describe the effects of depressants Tranquilizers, sedatives and hypnotics, which calm and relax; they slow down heart rate and breathing. Tranquilizers include alcohol, Valium and Librium and are weaker than the others. These relieve anxiety and tension. Sedatives: Barbituates that soothe distress without producing much sleep in small doses. Hypnotics: Like chloral hydrate. These induce sleep. Too much can lead to coma or teach. B.4.2. Discuss the social and physiological effects of the use and abuse of ethanol. Social effects: Major costs from alcohol are from sickness and death, as in hospital treatments and lost efficiency. Property crimes and crimes against people; drinking while driving. Physiological effects: Harmful to relationships, and may physically or emotionally harm others. One may lose control and develop dependence and tolerance. It increases blood pressure when drinking and nausea, sweating and anxiety as withdrawal of use. Short-term effects: CNS depressant reduces tension. It triggers Euphoria, Talkativeness, Dilation of blood vessels, Violent behaviours, Inertia, Coma, Death. Long term effects: Cirrhosis, liver cancer, coronary heart disease, high blood pressure, strokes, gastritis, low birth mass etc. Alcohol can be used for antiseptics such as mouthwashes. B.4.3. Describe and explain the techniques used for the detection of ethanol in the breath of in the blood or urine. Ethanol passes from the stomach into the blood and therefore it passes into the lungs and ethanol vapour is formed. The breathalyser test might involve a redox equation with potassium dichromate: as oxidizing agent. Color change: Red-Orange to Green The gas liquid chromatography works as follows: Small samples of gases and volatile liquids such ethanol are separated. These are pushed through a column using an unimportant gas, such as Nitrogen gas and different gases take different time to come to the detector, where concentration of gases are measured. Intoxilyzer, Infra-red spectroscopy: Infra-red energy make molecules vibrate. Different types of bonds absorb and vibrate at different infer-red frequencies. By measuring how much energy is not absorbed by the molecules, one can find the number of certain bonds in the molecules. B.4.4. Describe the synergistic effects of ethanol with other drugs. Alcohol is easily absorbed in the stomach, so drugs that can be dissolved in alcohol will be absorbed much quicker, and the dosage will seem higher as in normal conditions the liver removes a part of the drug. So performance of the drug is enhanced and may lead to devastating effects such as death, especially if alcohol is combined with barbituates. Alcohol with aspirin increases the risk of stomach bleeding. B.4.5 . List other commonly used depressants and describe their structures. Valium (diazepam) is a tranquilizer, Mogadon (Nitrazepam) is a hypnotic drug (used to control seizures and infantile spasms), Prozac (hydrochloride) is an anti-depressant drug used to treat mental depression. Diazepam and Nitrazepam have similar carbon skeletons meanwhile Prozac is different. B.5.1. List the physiological effects of stimulants. Stimulants are chemicals that stimulate the brain and the central nervous system. It is the opposite of a depressant. These increase alertness. Examples are amphetamine, nicotine and caffeine. B.5.2. Compare amphetamines and adrenaline They both derive from the phenylethylamine structure, and therefore look similar. Furthermore, amphetamines mimic the effects of adrenaline (they are sympathomimetic drugs), as they constrict arteries and thus increases sweat production. They increase heart rate, blood pressure, respiration and insomnia. Medical uses: Treat mild depression, narcolepsy and asthma. They use up the body’s reserve energy and can lead to a collapse. B.5.3 Discuss the short- and long-term effects of nicotine consumption. Tobacco is a source of nicotine which is a mild stimulant with a short lived effect. The response is followed by depression and thereby makes one pushed to use it more often. Short-term: Increase in heart-rate and blood pressure. It constricts blood vessels and therefore strains the heart. Nicotine also reduces urine output. Long term effects of nicotine: It stresses hard and may lead to heart diseases and blood clot; May lead to increase of fatty acids in the blood. Smoking leads to more carbon monoxide in the blood making the blood less able to carry blood. It also increases the gastric acid production and may lead to ulcer. Smoking causes: Cancer in lungs and mouth; heart and blood vessel disease; breathing difficulties and chronic bronchitis; air pollution; fires; bad teeth; insomnia. B.5.4. Describe the effects of caffeine and compare its structure with that of nicotine. Caffeine stimulates the respiratory system (more energy is available from respiration), so heart and brain gets more energy. So one becomes more alert, motivated and well-being. In small amounts in is rather harmless, but too much causes insomnia. One gets more urine as well. Caffeine leads to some tolerance but no physical addiction. It can be given to babies to help their breathing. It also constricts blood vessels and therefore helps against migraines. Both caffeine and nicotine contain a tertiary amine group. Caffeine has more of those though. B.6.1. Describe the historical development of penicillins. In 1928, Fleming accidentally saw that some types of fungi killed off a certain bacterium and started to try to isolate the fungi, but it was too hard to purify it. In 1940, Floray and Chain continued with penicillin testing and development, and in 1943 it was available clinically. The first penicillin was Penicillin G. However it was deactivated by stomach acid so it had to be injected. Acid resistance penicillins such as penicillin V was developed by modifying the side chains of the basic penicillin structure. Some bacteria could deactivate penicillin G by synthesising an enzyme, therefore one had to make other synthetic penicillins. 6-APA penicillin is inert, but an extra amino group H2N would activate it. B.6.2. Compare broad spectrum and narrow spectrum antibiotics A broad spectrum antibiotics is effective against a wide variety of bacteria. Examples are tetracyclines. Narrow ones are effective only against certain types of bacteria; most penicillins are narrow spectrum antibiotics. One often has to determine the bacterium before getting antibiotics, because a broad-spectrum one can kill beneficial bacteria and give discomfort. B.6.3. Explain how penicillins work and discuss the effects of modifying the side chain. The cell walls of some bacteria are composed of polysaccharides, and these layers are supported by cross-links. However, penicillins interfere with the formation of these links and therefore weaken the structure. The bacteria can easily burst. Animals cells don’t have these cell walls and are therefore not affected. It is important to modify the side chain to work against bacteria have evolved and are able to break down certain types of penicillin. Side chains are also added to make the penicillin work (as for the 6-APA) and to survive the gastric acid (Penicillin G) B.6.4. Discuss and explain the effect over prescription of penicillins has, and the use of penicillins in animal feedstock Repeated use may lead to allergic reactions. They can also wipe out harmless and beneficial bacteria in the food canal, and harmful bacteria might eventually replace these. Bacteria can become resistant against certain antibiotics and then pass on their immunity. In feedstock: They are used to kill dangerous pathogens which may otherwise endanger humans and animals. They are also used to increase productivity. However, this increases the chances that bacteria might become resistant. B.7.1. State how viruses differ from bacteria Bacteria are relatively large single cell microorganism with DNA strands. Viruses are noncellular and are much smaller and are not living. They can only reproduce within a host cell. B.7.2. Describe the different ways in which antiviral drugs work * Block the transfer of genetic information * Control by inoculation, vaccines. * Block the enzyme activity in a host cell, so that the virus can’t use it to replicate. B.7.3. Discuss the difficulties associated with solving the AIDS problem HIV molecules bind to proteins on T-type of white blood cells and hinder them from fighting infections by inactivating them. HIV virus is good at mutating and together with their similarities with human cells, it is very heard to treat with antiviral drugs and vaccines. B.8.1. Describe the importance of geometrical isomerism in drug action. Stereoisomers are isomers with the same molecular formula and the same structural formula, but different arrangement of atoms in space. Geoemetric isomers have different physical properties such as polarity, boiling point, and solubility etc. They may also undergo different t chemical reactions although their functional groups are identical. For example cisplatin is en effective anti-cancer drug (as it may enter the nucleus of a cancerous cell), but the trans-isomers is inactive in such purposes. B.8.2. Discuss the importance of chirality in drug action. Optical isomers differ from geometric isomers in two ways: * Optical isomers are chiral (asymmetric) * Optical isomers are non-superimposable mirror images of each other One optical isomer rotates the plane polarized light one direction, meanwhile its other isomer rotates it the other way. An equi-molar mixture of two enantiomers means a 50-50 ration and will not totate the plane of polarised light at all; this is a racemic mixture. Penicillin V is active, but its enantiomer is inactive. One enantiomer of Thalidomide could be used to treat morning sickness in pregnant women and was marketed as a racemix mixture, but its other enantiomer gave foetal deformities. B.8.3. Describe the use of chiral auxiliaries to form the desired enantiomer. It is very heard to separate racemic mixtures into separate enantiomers, as they have identical chemical properties in relation to non-chiral reagents. Instead, scientists use stereospecific synthesis to produce only one kind of enantiomer. Chiral auxiliaries are used to convert non-chiral molecules into a desired enantiomer by attching itself chemically to the non-chiral molecule so that only one type of enantiomer can be formed. After the procedure the auxiliary can be recycled. This is used when synthesising Taxol which isa drug effective against breast cancer. B.8.4. Explain the use of combinatorial chemistry to synthesise new drugs. This is when one creates lots of molecules and test them quickly for biological properties; one starts with a set of basic chemicals which are then combined in all possible combinations, and this allows a fast production of many different molecules, increasing the chance of finding better drugs. A library is a collection of compounds that are screened to determine their usefulness as a drug, using parallel synthesis (identical processes with many different molecules at the same time). B.9.1. Compare local and general anaesthetics in terms of their modes of action Local anaesthetics block the pain in specific areas when they are injected under the skin or used as a crà ¯Ã‚ ¿Ã‚ ½me. Examples are cocaine, procaine, benzococaine, lidocaine etc. These block local nerve transmissions and decrease blood supply to that area. Procaine and lidocaine do not affect the brain, meanwhile cocaine does. General anaesthetics affect the brain and produce unconsciousness. But it is easy to reverse the unconsciousness. Examples are nitrous oxide, diethyl ether, chloroform, cyclopropane and halothane. B.9.2. Compare the structures and effects of cocaine, procaine and lidocaine. All three have the benzene ring and the tertiary amine. Cocaine also stimulates the central nervous system. It constricts blood vessels which leads to high blood pressure, and can’t be safely used. Although it doesn’t produce withdrawal symptoms and tolerance, it produces a strong psychological addiction. An overdose suppresses heart and respiration. Cocaine has a very short half life as it is metabolized by the liver fast, and is poorly absorbed when taken orally. Procaine gives prolonged relief from pain which is good for surgery and dental procedures. It is non-toxic and non-irritant. Lidocaine is used topically to produce numbness. It is more potent that procaine, but may cause swelling and itching. B.9.3. Discuss the advantages and disadvantages of nitrous oxide, ethoxyethane, trichloromethane, cyclopropane and halothane. Nitrous oxide is not very potent, and makes one feel good Trichloromethane is nonflammabe, but leads to liver damages. Narrow safety margin Ethoxyethane alleviates the pain in surgery well, but it is very flammable and nonstable. Cyclopropane is a very potent anaesthetics, however it forms explosive mixtures with air and is very flammable. It also causes vomiting and nausea. Halothane is widely used as it is not flammable and one may recover fast from it. It doesn’t irritate the respiratory tract. However, it takes time to become unconscious. It is potentially harmful to the ozone layer as it produces chlorine and bromine free radicals. B.9.4. Calculate the partial pressures of component gases in an anaesthetic mixture The partial pressure ratios of the total pressure equal the molar ratios of different gas molecules. It is important to have enough oxygen in the anaesthetic mixture so that the patient can live. At least 20% oxygen is needed B.10.1 Describe the effects of lysergic acid diethylamide (LSD), mescaline, psilocybin and tetrahydrocannabinol. Psychadelic drugs like these alter the mind and produces a change in thought, perception or mood and induce vivid fantasies. Colors seem more brilliant for the user. There are the effects of the mentioned mind altering drugs: LSD: This is a powerful hallucinogen that strongly magnifies perception and may destroy the sense of judgment. No physical addiction, and not very strong psychological dependence. Mescaline: Color hallucinations which last 12 hours. Psilocybin: Similar to LSD, especially at high doses, but at low doses produces relaxation. Shortlasting; 4 hours THC: Milder drug similar to alcohol. At larger doses, changes in perception occurs – sees bright colors and gets sharper hearing. May get extreme anxiety, depression, uneasiness, panic attacks etc. There is no tolerance, but could lead to psychological dependence. B.10.2 Discuss the structural similarities and differences between LSD, mescaline and psilocybin. LSD and psilocybin both have the Indole ring (Heterocyclic amine compound where the nitrogen atom is part of a ring). However, mescaline includes the benzene ring but not the indole ring; it does have a primary amine. Serotonin also has the indole ring. B.10.3 Discuss the arguments for and against the legalization of cannabis. Cannabis offers relief from symptoms from AIDS, cancer and glaucoma. Marijuana may increase the appetite, and relieves nausea. Cannabis helps terminally ill patients to relieve tension and anxiety. Marijuana relieves pressure inside the eyeball for glaucoma patients. However there are many bad sides to it too. Smoking marijuana may lead to lung problems and may suppress the immune system. It might lead to decreased fertility for men and cause brain damage and birth defects. Users may also start using harder drugs too. Users of prohibited drugs need to obtain it from criminal sources and may therefore be forced into crime to support their habit. It damages the society a lot.

Quantitative Techniques

Classification of Quantitative Techniques: There are different types of quantitative techniques. We can classify them into three categories. They are: 1. Mathematical Quantitative Techniques 2. Statistical Quantitative Techniques 3. Pprogramming Quantitative Techniques Mathematical Quantitative Techcniques: A technique in which quantitative data are used along with the principles of mathematics is known as mathematical quantitative techniques. Mathematical quantitative techniques involve: 1. Permutations and Combinations: Permutation mearns arrangement of objects in a definite order.The number of arrangements depends upon the total number of objects and the number of objects taken at a time for arrangement. The number of permutations or arrangements is calculated by using the following formula:=  Ã‚  Ã‚   n! n r ! Combination mearns selection or grouping objects without considering their order. The number of combinations is calculated by using the following formula:=  Ã‚  Ã‚   n! n r ! 2. Set Theory:Set theory is a modern mathematical device which solves various types of critical problems. Quantitative  Techniques  for  Business     Ã‚  5 School  of  Distance  Education 3. Matrix Algebra:

Evaluation of The Poverty Issue in US Economy Essay - 5

Evaluation of The Poverty Issue in US Economy - Essay Example There is little contradiction as to objectives, for example; the proceeding with verbal confrontation in the middle of liberals and preservationists is not over closures; it is over means (Cypher, 2014). Presently, the characteristic approach to attaining to the economic ends of higher living standards, one would assume, is by utilizing financial means and getting to be more profitable. It is just in a profitable, prosperous economy that imparts the riches projects bode well whatsoever; and it is just by growing the systems which clarify our present flourishing that the less prosperous may want to enhance their circumstances. Government is not an economic institution; administrative activity, all things considered, does not deliver sustenance, garments, or asylum (Gordan, 2005). The provisioning of men's material needs includes financial activity, with government remaining by to secure the maker and keep the exchange courses open. The government has no monetary products of its own, so any riches it offers on either individual must first be gotten from the people who delivered it. If the government gives Peter a dollar, it should first deny Paul of a bit of his profit. The way of political activity is such that legislature cant in any way, shape or form be utilized as a lever to raise the general level of monetary, physical, and intelligent prosperity. Let us attempt to get this matter of poverty into a point of view. The greater part of individuals has had some experience with destitution. The majority of people encountered destitution in their particular families or, at any rate, in the neighborhoods. In the 1930s, there were many men without occupations (Louis & Jennings, 1999). However, amid this same period, the nineteen thirties, more than five million individuals passed on of starvation in Ukraine; in no way like this happened in America.